What type of color defect would macular degeneration most likely cause according to Kollner's Rule?

Macular degeneration primarily affects the central part of the retina, which is responsible for sharp vision and color perception. According to Kollner's Rule, the type of color vision defect caused by retinal diseases typically involves the blue/yellow axis. This is due to the fact that the macula contains a higher density of cone cells, which are responsible for color vision, particularly those sensitive to shorter wavelengths (blue).

In the case of macular degeneration, the loss of function in these cones leads to a disturbance in how blue and yellow are perceived, often resulting in a blue/yellow color defect. The more common red/green defects are generally associated with optic nerve or central nervous system issues rather than retinal damage, following the principles outlined in Kollner's Rule.

Thus, macular degeneration would most likely cause a blue/yellow color defect, aligning with typical patterns of color vision deficiencies caused by disturbances in the retinal layers.